Abstract
Polioencephalomalacia (PEM) is a nervous disease with neuronal necrosis. He previously believed that this condition was related to thiamine deficiency, but studies suggest that it can be determined by different nutritional and dietary factors. In this context, objectified to perform a literature review on the main causes of polioencephalomalacia caused by nutritional and dietary factors as well as the appropriate treatment and prevention in ruminants. Therefore, PEM disease can be caused by the classic thiamine deficiency, lead poisoning, sulfur and salt associated with drinking water deprivation. To prevent PEM, avoid contaminated material in pastures (avoid lead and sulfur), invasive plants (avoid thiaminases) and nutritional management of dietary thiamine concentrations and sulfur levels in water and diet. For treatment it is recommended to identify the source that causes the disease, deprivation of contaminated material and use of food management techniques, drugs needed to restore the metabolic parameters.
Highlights
Polioencephalomalacia (PEM) is a designative term for the morphological diagnosis of softening necrosis of the brain gray matter and cerebrocortical necrosis is the term used to designate the same pathological condition in Europe (MARKSON et al, 1972; EDWIN et al, 1979; JEFFREY et al, 1994).The term “polioencephalomalacia” was first used in Colorado in the United States in 1956 to denote an injury, but a specific ruminant disease, primarily caused by thiamine deficiency and characterized by necrosis of the telencephalic cortex (JENSEN et al, 1956).it is known that not all cases associated with polioencephalotomalacia (PEM) in ruminants are related to thiamine deficiency
Polioencephalomalacia (PEM) is a nervous disease with neuronal necrosis. He previously believed that this condition was related to thiamine deficiency, but studies suggest that it can be determined by different nutritional and dietary factors
PEM disease can be caused by the classic thiamine deficiency, lead poisoning, sulfur and salt associated with drinking water deprivation
Summary
Issue ID: Sci. Elec. Arch. Vol 13 (4) April 2020 DOI: http://dx.doi.org/10.36560/13420201042 Article link http://sea.ufr.edu.br/index.php?journal=SEA&page=article&o p=view&path%5B%5D=1042&path%5B%5D=pdf Included in DOAJ, AGRIS, Latindex, Journal TOCs, CORE, Discoursio Open Science, Science Gate, GFAR, CIARDRING, Academic Journals Database and NTHRYS Technologies, Portal de Periódicos CAPES.
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