Abstract

The ApoE4 allele is a well-studied genetic risk factor for Alzheimer's disease, a condition with increasing prevalence and no cure. Precision nutrition, which targets metabolic pathways affected by ApoE4, offers a potential tool for disease prevention. However, long-term human studies on effective nutritional protocols for preventing Alzheimer's in ApoE4 carriers are lacking, partly because the precise mechanisms underlying the increased dementia risk in carriers are not fully understood. Fortunately, recent research has shed light on these mechanisms, opening up opportunities for potential risk reduction through lifestyle and nutrition interventions. In this research paper we discuss about the chawanprash phytocompounds and it is found that Terchebin is the effective phytocompund though docking and simulation methods and thereby indicating the potent Nutraceutical against various Neurological manifestations that is caused due to SARS Cov2 and AD. In this review, we explore recent findings on how ApoE4 impacts various cellular processes, including microglia and other inflammatory pathways.

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