Non-toxic Cs3Bi2Br9 quantum dots molecular imprinted nanocomposite with boronate affinity and imprinting selectivity for selective detection of oxytetracycline

Abstract

In this work, a non-toxic bismuth-based perovskite quantum dot fluorescent nanocomposite (Cs3Bi2Br9@SiO2-MIPs) was constructed for the detection of trace oxytetracycline (OTC) in the ethanol phase, which solves the toxicity problem of perovskite quantum dots and realises the application of non-toxic perovskite quantum dots in analysis and detection, the combination boronate affinity effect and molecularly imprinted technology enables highly selective detection of the Cs3Bi2Br9@SiO2-MIPs. The basic structure and optical properties of Cs3Bi2Br9@SiO2-MIPs were characterized by various characterization methods, and the optimal detection conditions and fluorescence detection ability of Cs3Bi2Br9@SiO2-MIPs for OTC were determined. Under the optimal conditions, the Cs3Bi2Br9@SiO2-MIPs had a good linear relationship with OTC in the concentration range of 0.8 ∼ 130 μM, and the detection limit was 0.32 μM. Furthermore, the fluorescence detection mechanism of the Cs3Bi2Br9@SiO2-MIPs was investigated in detail, which ultimately revealed that the detection mechanism was a synergistic effect of inner filter effect and fluorescence resonance energy transfer. The Cs3Bi2Br9@SiO2-MIPs was successfully applied to the detection of trace OTC in real samples. This work provides a new idea for the construction of environmentally friendly and highly selective perovskite quantum dot fluorescent nanocomposite.