Abstract

We have studied the effect of a particular kind of non-Gaussian noise (NGN), mainly of its deviation q from Gaussian noise, on the intercellular calcium (Ca2+) oscillations in an array of bidirectionally coupled cells. It is found that as q is increased, the Ca2+ oscillation becomes the most regular at an intermediate optimal q value, representing the occurrence of coherence resonance (CR). This deviation-induced CR behavior shows that the intercellular Ca2+ oscillations of the coupled cells can be enhanced and even optimized by the appropriate NGN. This result provides a new insight into the constructive role of the NGN on the transmission of Ca2+ signaling in coupled cells.

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