Abstract
NMR microscopy is usually achieved at ultra-high-static magnetic field (9.4 Tesla) with the use of home-built coils adapted to the size of the sample. In that way, well-resolved images can be obtained with voxel size smaller than 50 m. The purpose of this article is to show that high-resolution imaging can be realized at lower field strength (4.7 Tesla) using 5- and 10-mm probes initially dedicated to vertical magnets. These coils are easily adaptable to horizontal imaging systems. Excellent quality and filling factors permitted isotro- pic resolutions (50 m) on a biomaterial and on mouse femoris. This study also demonstrates that spoiled-gradient echo sequence (FLASH) with low reception bandwidth or with the use of gadolinium are particularly effective for 3D MR microscopy. © 2005 Wiley Periodicals, Inc.
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