Abstract
The ribosomal elongation cycle represents a series of reactions during which the polypeptide is prolonged by one amino acid and after which the prolonged polypeptidyl residue is again ready to accept the next aminoacyl residue. It is generally believed that the ribosome carries two tRNA binding sites, the A site for aminoacyl-tRNA and the P site for peptidyl-tRNA, leading to the classical two-site model of the ribosome as a description for the elongation cycle. However, evidence is accumulating which is in conflict with the classical two-site model. These conflicts are resolved in a new three-site model which is discussed in detail in this paper.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
