Abstract
Necrotizing sialometaplasia is a benign, uncommon, self-limiting lesion of salivary glands that can be clinically mistaken for mucoepidermoid or squamous cell carcinoma. A 64-year-old male patient was referred with a painful deep necrotic ulcer on the midline of the hard palate and measuring 3 cm in diameter. The patient stated that the ulcer grew progressively over a month. He had a history of smoking and denied any other medical history or local trauma. An incisional biopsy was performed, and the histopathologic examination showed ulcerated mucosa, granulation tissue, and mixed inflammatory cell infiltrate in the underlying connective tissue. One week later, the patient reported that the necrotic tissue detached from the lesion spontaneously, and a new biopsy was taken. This time, the histopathologic examination confirmed the diagnosis of necrotizing sialometaplasia. Three sessions of photobiomodulation therapy were performed, and at the 10-month follow-up, there was a complete healing of the lesion.
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