Abstract
Purpose: To investigate how activity of natural pupils under binocular and monocular conditions affect wave front aberrations. Materials and Methods: Eighteen eyes from 18 subjects (mean age 22.3 ± 0.8 years) were included in the study. The undilated pupil diameters under photopic conditions were measured using the FP-10000 (TMI, Japan) infrared pupillometer. Aberrometry measurements were performed using the KR-9000PW (Topcon, Japan) Hartmann- Shack wavefront sensor. Zernike coefficients were recalculated for the diameters of each pupil under binocular and monocular conditions using Schwiegerling’s algorithm. Multiple regression analysis was performed to analyze independent predictors of the change of higher-order aberration for 6.0 mm from the binocular to the monocular condition. The independent variables were the change of pupil diameter from binocular to monocular condition; binocular pupil diameter; total higher-order aberration for 6.0 mm, sphere, and cylinder. Results: Pupil diameter, total, total higher-order, coma-like, and spherical-like aberrations under monocular conditions were significantly greater than the binocular condition (all P<0.01). The multiple regression of analysis of variables showed that the change of total higher order aberration from the binocular to the monocular condition was related to the change of pupil diameter, and the amount of higher-order aberrations for 6.0 mm (P<0.05). Conclusion: The outcomes suggest that increased pupil diameter under monocular conditions produces higher wavefront aberrations than under binocular conditions, resulting in a degradation of retinal image quality. This effect is enhanced in eyes with greater higher order aberrations and pupil diameter
Highlights
The effect of pupil diameter is being incorporated into cataract surgery, refractive surgery [1,2,3,4] and the contact lens fittings [5]
Pupil diameter, total, total higher-order, coma-like, and spherical-like aberrations under monocular conditions were significantly greater than the binocular condition
The multiple regression of analysis of variables showed that the change of total higher order aberration from the binocular to the monocular condition was related to the change of pupil diameter, and the amount of higher-order aberrations for 6.0 mm (P
Summary
The effect of pupil diameter is being incorporated into cataract surgery, refractive surgery [1,2,3,4] and the contact lens fittings [5]. Visual performance is simulated for monocular conditions pupil diameter under monocular conditions is greater than under “real life” binocular conditions [8]. This pupilenlargement effect leads to an increase in the optical aberrations, the evaluation of visual performance under binocular conditions is important. A number of studies have advocated the importance evaluating post-refractive surgery patients under binocular conditions [9,10,11,12] It is unclear how this change in physiologic pupil diameter between binocular and the monocular conditions affects the increase in ocular wavefront aberrations or whether the change depends on pupil size, the magnitude of higher-order aberration, or refractive error
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