Abstract
This study investigates the phytochemical profile, total flavonoid content, antibacterial properties, antioxidant activities, and cytotoxicity effect of nanoemulsion ethanolic extract of Sungkai leaves. The ethanolic extract was formulated into three concentrations: 50, 100, and 150 ppm. Phytochemical screening revealed flavonoids, tannins, alkaloids, steroids, and terpenoids. The total flavonoid content was 90.542, 91.993, and 91.744% for the respective concentrations. Antibacterial activity against Propionibacterium acnes showed inhibition zones of 17.6, 21.2, and 24.1 mm, indicating strong to very strong activity. Antioxidant activities, evaluated using DPPH, ABTS, and FRAP assays, showed IC50 values categorized as very strong. The cytotoxicity test exhibited moderate activity. These findings suggest that Sungkai leaf ethanol extract nanoemulsion has rich bioactive compounds with significant antibacterial and antioxidant properties, along with moderate cytotoxic activity, highlighting its potential for pharmaceutical and cosmetic applications.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
