Abstract

Objective To explore the clinical effects of Naloxone combined with Citicoline treatment for hypoxie-ischemic eneephalopathy.Methods 98 cases of hypoxie-isehemic eneephalopathy patients were divided into observation group and control group,49 cases for each group,the control group was treated with the combined treatment about supportive treatment,composure,lowering intracranial hypertension,correcting acidosis and using brain cell metabolism medicine and so on,and Citicoline was added for treatment.The observation group was treated with the sanle way of the control group,and adding Naloxone.Results The total effective rate of observation group was 91.84%,while the control group was 65.31%,there were statistical significance between them(P<0.05). Conclusion The Naloxone combined with Citicoline treatment for hypoxie-ischemic encephalopathy has botter effects without adverse reaction,it can improve the cure rate,reduce the disability rate,worthy for clinical application. Key words: Hypoxie-ischemic encephalopathy; Naloxone; Citicoline

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