Impact of Shuxuetong combined with oxiracetam on NIHSS and MMSE scores of patients with cerebral hemorrhage

Abstract

Objective To study and analyze the impact of Shuxuetong combined with oxiracetam on the NIHSS and MMSE scores of patients with cerebral hemorrhage,and to explore the efficacy of the treatment.Methods 98 patients with cerebral hemorrhage were chosen from our hospital from April,2012 to April,2013 and were randomly divided into an observation group and a control group,49 cases for each group.All patients received regular medication,such as fructose,mannitol,and glycerol symptomatic treatment and rehabilitation training.In addition,the control group were treated with citicoline sodium,and the observation group with Shuxuetong and oxiracetam.Three weeks after the treatment,the NIHSS and MMSE scores,the hematoma volume,the surrounding low-density district condition,and adverse reactions were compared between the two groups.Results The NIHSS and MMSE scores were (2.23 ± 1.96) and (27.08 ± 6.12) 3 weeks after the treatment and were (7.15 ± 4.68) and (16.32 ± 5.40) before the treatment in the observation group and were (3.91 ± 2.87) and (21.76 ± 5.95) 3 weeks after the treatment in the control group,respectively,with statistical differences (P ＜ 0.05).After the treatment,the hematoma volume and the range of surrounding lowdensity district declined in both groups,but declined more in the observation group than in the control group,with statistical differences (P ＜ 0.05).There were no statistical differences in adverse reactions between the two groups (P ＞ 0.05).Conclusions Shuxuetong combined with oxiracetam in the treatment of cerebral hemorrhage has significant effect,can significantly improve the neurological symptoms,and is worth being clinically recommended. Key words: Shuxuetong; Oxiracetam; Cerebral hemorrhage; NIHSS; MMSE