Abstract
The pH values of endolymph in the inner ear of guinea pigs were studied with the use of H+ selective double-barreled microelectrodes. The pH in the endolymph was similar in the cochlea (7.54±0.06, n=12), in the saccule (7.54±0.04, n=7) and in the utricle (7.53±0.06, n=7) under different DC potentials in each endolymphatic space. The intravenous injection of ethacrynic acid resulted in a significant increase of pH value in the cochlea but not in the saccule and the utricle. The possibility that different mechanisms producing the endolymph pH may exist in different parts of the inner ear is discussed.
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