Abstract
The distribution pattern of alkaline phosphatase in the inner ear of fetuses, newborn and adult guinea pigs is described. In the inner ear of fetuses, remarkable alkaline phosphatase was noted throughout the entire tissue of spiral ligament, statoacoustic nerve fibers and the wall of small blood vessels. In newborns, however, less enzyme activity was seen in the spiral ligament and statoacoustic nerve. In adult guinea pigs, no enzyme activity was detectable in the spiral ligament and statoacoustic nerve fibers except for the wall of small blood vessels and efferent nerve fibers. It is evident that the distribution pattern of alkaline phosphatase is altered during the development of the inner ear of the guinea pig.
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