腹腔鏡下卵巣チョコレート嚢胞摘出術後の再発リスク因子についての検討

Abstract

Objective: To evaluate risk factors associated with ovarian endometrioma recurrence after laparoscopic cystectomy.Design: A retrospective study.Setting: Minoh City Hospital.Patients: This study included 81 women who underwent laparoscopic cystectomy for ovarian endometrioma and were followed up postoperatively for more than 4 months. Interventions: Laparoscopic cystectomy and postoperative medical treatment.Main outcomes: Eighteen variables (age at surgery, body mass index, age at menarche, parity, infertility, pain, previous surgery for ovarian endometriosis, previous medical treatment of endometriosis, tumor marker, size of the largest cyst, single or multiple cysts, unilateral or bilateral involvement, laterality [left or right], revised American Society for Reproductive Medicine [r-ASRM] score, r-ASRM stage, uterine myoma, postoperative medical treatment, and postoperative pregnancy) were evaluated to assess their effects on the risk of ovarian endometrioma recurrence.Results: The recurrence rate was 12.3% (10/81 patients). The 5-year cumulative recurrence rate was 37%. The size of the largest cyst, presence of multiple cysts, and previous medical treatment were associated with ovarian endometrioma recurrence. The recurrence rate was significantly lower in the women who received postoperative medical treatment (3.3%) than in the women who did not receive medication (20.6%).Conclusion: In this study, the size of the largest cyst and the presence of multiple cysts were associated with ovarian endometrioma recurrence after laparoscopic cystectomy. The continuous postoperative medical treatment decreased the risk of ovarian endometrioma recurrence.