Myocardial amyloidosis combined with atrial giant thrombosis secondary to multiple myeloma: A case report

Abstract

Introduction: Multiple myeloma (MM) is a hematologic disorder that is relatively common in the elderly population. Given the rapid development, limited survival, and poor prognosis of the majority of patients, a definitive, prompt diagnosis is critical for treating individuals with multiple myeloma accompanied with cardiac amyloidosis. The incidence of myocardial amyloidosis with MM, relatively speaking, is low and early clinical manifestations are nonspecific. Atrial thrombi, with low detection, are a hallmark of poor prognosis of patients diagnosed MM with amyloidosis cardiomyopathy. Case Report: Aiming to serve as useful feedback information for judging the prognosis of target patient, we now analyzed the clinical data of an elderly female with atrial thrombi as the main symptom and impaired cardiac function combined with echocardiography electrocardiography (ECG), laboratory data, cell Congo Red staining and other manifestations to diagnose amyloidosis combined with MM. Conclusion: The formation of atrial thrombi is closely related to the prognosis of myocardial amyloidosis and in order to identify atrial thrombi early and to intervene early, transesophageal ultrasound should be included as part of routine investigations in patients with myocardial amyloidosis.