Abstract
Objective To study the clinical characteristics of patients with cardiac amyloidosis(CA)caused by multiple myeloma. Methods Methods In this paper, 8 patients with myocardial amyloidosis caused by multiple myeloma were collected, who were admitted to Beijing Friendship Hospital, Capital Medical University from 2009 to 2017.The clinical characteristics of CA patients were analyzed. Results Clinical manifestations of patients with myocardial myeloma caused by multiple myeloma are diversified, often have cardiac insufficiency and have clinical manifestations outside of the cardiovascular system.Low voltage in limb lead and hypertrophy in left ventricular are the characteristic changes of CA.Cardiac magnetic resonance imaging(MRI)presented gadolinium delay imaging, which has high positive rate in diagnosis of CA.The golden standard for diagnosis of CA is the positive of Congo Red stain in endomyocardial biopsy. Conclusions CA diagnosis can be confirmed by biopsy of exocardial tissue in combination with electrocardiograph, ultrasonic cardiogram and MRI.The progression is different of CA, but generally with poor prognosis due to lack of effective treatment. Key words: Amyloidosis; Multiple myeloma; Disease attributes
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