Abstract

SINCE Stroebel and Hazen in 1911 studied sections of biopsy material of skin in mycosis fungoides and described what they called typical mycosis cells as ``measuring from 8-10 microns in diameter and having an eccentric nucleus, the diagnosis of the disease has depended on the finding of these cells. 1 As hematologists, we have been interested primarily in cytology, and our interest has not been confined to the study of blood cells. Starting with the aspiration of bone marrow, we have evolved a simple technique for diagnosis of various diseases, at first, by aspiration from the spleen in many hematological disorders, notably osteosclerotic anemia, 2 Gaucher's disease, Hodgkin's disease, and Boeck's sarcoid, 3 thence to aspiration of lymph nodes for similar hematological disorders, 4 as well as for such malignant conditions as metastatic carcinoma and lymphosarcoma. 5 Our search for cytological material was extended to accessible tumors

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