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Open Accesshttps://doi.org/10.1158/2767-9764.crc-24-0400
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Cite Journal: Cancer research communications |  Publication Date: Feb 1, 2025 |
 License type: cc-by |
We show that HSF1 and MYC genes are co-amplified in more than 30% of HGSOC and demonstrate that HSF1 and MYC functionally cooperate to drive the growth of HGSOC cells. This work provides the foundation for HSF1 and MYC co-amplification as a biomarker for treatment efficacy of the polo-like kinase 1 inhibitor volasertib in HGSOC.
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