Abstract

Psilocybin (O-phosphoryl-4-hydroxy-N,N-dimethyltryptamine) and related compounds have been isolated from more than 150 species of mushroom but are primarily found in the following genera: Psilocybe, Panaeolus, Gymnopilus. The species most commonly referenced in the literature are: Psilocybe cubensis, Psilocybe mexicana, Psilocybe cyanescens, Psilocybe semilanceata; Panaeolus foenisecii; Gymnopilus spectabilis; Psathyrella foenisecii. The family of psilocybin-containing mushrooms grows in tropical and subtropical regions of South America, Mexico, and the United States. Hallucinogenic varieties of Psilocybe were used by prehistoric peoples for religious and healing purposes. Today most individuals consuming psilocybin mushrooms are intentionally seeking a psychedelic experience.

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