Multislice spiral CT findings and its diagnostic value of mixed glandular glass nodular adenocarcinoma

Abstract

Objective To analyze the characteristics of mixed ground glass nodular adenocarcinoma in multi-slice spiral CT(MSCT) and its diagnostic value. Methods This study was prospective study, 120 patients with mixed glass nodules lung adenocarcinoma were classified as lung adenocarcinoma in the People's Hospital of Xinzhou from January 2014 to December 2016.178 cases of mixed glass nodular pneumonitis were classified as pneumonia.The MSCT signs were compared between the two groups.The imaging features of medullographic nodules with different pathologic types of lung adenocarcinoma by grouping of patients with lung adenocarcinoma were compared. Results In the lung adenocarcinoma group, the dizzy uneven thickness rate(61.67%), leaf rate(60.00%), clear boundary rate(80.83%), blood vessels, gather tax rate(64.17%), pleural indentation rate(61.67%) were significantly higher than those in the pneumonia group(35.96%, 35.39%, 41.01%, 44.94%, 41.57%, χ2=8.69, 12.47, 33.64, 7.62, 7.97, all P<0.01). The mixed grinding glass nodules of IAC, MIA and MIS in size, number, shape, position and density were significantly different(all P<0.05). The IAC type mixed grinding glass nodules was irregular single nodules(volume generally≥5 mm), common deviation centricity growth, and with blood vessels.The AIS type mixed grinding glass nodule was single nodule(volume generally≥5 mm), formed a polygon or dotted, common growth of centricity, vascular density was close to the same level.The volume of the MIA type mixed grinding hyaline nodules was most <5 mm, common to multiple, with oval or round most, common to deviate from the centricity growth, lower density than plane tree blood vessels. Conclusion MSCT is helpful in the differential diagnosis of mixed ground glass nodules of lung adenocarcinoma and mixed ground glass nodular inflammatory lesions, and pathological types have leaded to the identification of mixed ground glass nodules of lung adenocarcinoma MSCT, which has higher application value. Key words: Lung neoplasms; Adenocarcinoma; Tomography, spiral computed; Diagnosis