Abstract
Biosynthesized nanomaterials are in high demand due to their potential in medical applications and the search for efficient biosynthesized nanomaterials continues. The endeavor of this research work is to synthesize silver nanoparticles (Ag-NPs) utilizing an aqueous extract of Smilax aspera (S. aspera) leaves. Several analytical techniques were used to investigate the shape, morphology and size of NPs. UV–visible spectroscopy exhibited a band at 472 nm indicating the formation of Ag-NPs, phytoconstituents functioning as capping or reducing agent are revealed by FT-IR, XRD (X-Ray diffraction) verified cubic crystalline structure having (h,k,l) values at (1 1 1), (2 0 0), (2 2 0), (3 1 1) and (2 2 2). Energy dispersive X-rays spectroscopy confirmed the purity of elemental silver, Scanning electron microscopy as well as Transmission electron microscopy (TEM) reported that particles are in a spherical shape with a normal particle size of 34 nm. Furthermore, in DLS data two peaks at 5.89 nm (5%) and 39.99 nm (95%) were observed, which supports the TEM finding. The Synthesized Ag-NPs have shown significant antibacterial activity against pathogens due to the capping of the bioactive components of Smilax aspera leaves. Furthermore, The antioxidant potential of synthesized Ag-NPs was calculated performing 2,2 diphenyl-1-picrylhydrazyl hydrate (DPPH) free radical scavenging assay. Moreover, Methylene blue, Rose bengal, and Acridine orange dyes have also been degraded employing Ag-NPs as a catalyst. Inhibition of carbohydrate hydrolyzing enzymes, in addition to the previously mentioned actions, emphasized the antidiabetic efficacy of these produced Ag-NPs. Overall, Ag-NP’s efficient bioactivities indicate their promising future in biomedical and environmental remediation applications.
Published Version
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