Abstract
In the current exploration, photochemical stability and chemotherapeutic appraisal of Cinnamomum camphora (C.camphora) mediated bioactivity via Tellurium/Zirconium nanoparticles (TeZr BNPs) were conducted. The bioactive bimetallic nanoparticles (BNPs) exists a characterization by employing various studies such as UV, XRD, SEM-EDX, DLS, FTIR, HR-TEM, AFM, BET, and XPS analysis. Screening analysis of methanol soluble components in C. camphoraextract identified the components in the plant product by HPLC mass spectroscopy. Furthermore, inhibition activities of TeZr BNPs against monoderm (+) and diderm (−) pathogens were tested by the agar contact method. The results of these studies showed the maximum hindrance zone with TeZr BNPs against three different microorganisms:Staphylococcus aureus (ATCC6538), Escherichia coli (ATCC 8739), and Vibrio cholera(ATCC 14033) showing 28 %, 26 %, and 27 % inhibition, respectively, confirming the inhibitory potential of TeZr BNPs. The sequences of the inhibition zones were as follows: Staphylococcus aureus > Escherichia coli > Vibrio cholera. Further, the cytotoxic potential of C. camphora mediated TeZr BNPs was evaluated by anticancer, antioxidant, and anti-inflammatory activities. The photolysis steadiness of bioactive TeZr BNPs towards photodynamic therapy was confirmed by collagen degradation. This is the first description of bimetallic nanoparticles for degrading collagen. Hence, TeZr BNPs can be effectively applied in photodynamic therapy.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call