Abstract
Objective: In this study we aimed to compare blood count parameters such as; mean platelet volume (MPV), platelet count (PC), and platelet distribution width (PDW), white blood count (WBC), hemoglobin (HMG), hematocrit (HCT), lymphocyte (LYM ), neutrophil (NEU), PC/MPV, PC/LYM, PC/WBC, NEU/LYM rates; between healthy pregnant women and pregnant women with Gestational Diabetes Mellitus (GDM) whether these parameters have a predictive value of GDM. Methods: A retrospective case control study was performed and a total of 202 pregnant women including 78 pregnant women with GDM (38.6%) and 124 healthy pregnant women (61.4%; the control group) were fallen under the study. Prior medical histories had no particularity. Results: The result of compared parameters between GDM and Control Groups; there was no significant difference between any variables except age (p=0.024; p<0.05). Conclusion: If blood samples are evaluated under healthy conditions ( rapidly collection, transfer and studying) we concluded that blood count parameters would not be useful for predicting the diagnosis of GDM.
Highlights
Gestational diabetes mellitus (GDM) is defined as glucose intolerance diagnosed for the first time in pregnancy [1]
Gestational week, fasting blood glucose,75 gr Oral Glucose Tolerance Test (OGTT) 1st hour and 75 gr OGTT 2nd hour levels were examined, they were statistically higher in GDM group according to the control group
Some of them observed that mean platelet volume (MPV) values were significantly higher in GDM group than the control group, some of them found that MPV values were lower in GDM group, while some studies reported that there was no relationship between two groups for MPV value
Summary
Gestational diabetes mellitus (GDM) is defined as glucose intolerance diagnosed for the first time in pregnancy [1]. The correct definition and treatment of diabetes mellitus during pregnancy is very important due to perinatal morbidity and mortality as well as the long-term complications of mother and fetus [3]. For this reason, the diagnosis of GDM is very important for mothers and their babies. The average platelet volume (MPV), an easy and cost-effective parameter obtained from routine blood counts, which is often used to assess platelet morphology and can be used as an indicator of platelet activity [9]. On the other hand; the platelet count (PC), the PC to MPV ratio, and platelet distribution width (PDW) are the other platelet function parameters [1012]. In this study; we compared MPV, PC, PDW, white blood count (WBC), hemoglobin (HMG), hematocrit (HCT), lymphocyte (LYM ), neutrophil (NEU), PC/MPV, PC/LYM, PC/WBC, NEU/LYM rates between GDM and healthy pregnant women to evaluate prediction of GDM
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