MP45-06 THE CLINICAL PROFILE OF MEN WITH PREMATURE EJACULATION AT PRESENTATION HAS CHANGED OVER THE LAST FIFTEEN YEARS: ANALYSIS FROM A LONGITUDINAL STUDY

Abstract

You have accessJournal of UrologyCME1 Apr 2023MP45-06 THE CLINICAL PROFILE OF MEN WITH PREMATURE EJACULATION AT PRESENTATION HAS CHANGED OVER THE LAST FIFTEEN YEARS: ANALYSIS FROM A LONGITUDINAL STUDY Luca Boeri, Edoardo Pozzi, Federico Belladelli, Giuseppe Fallara, Simone Cilio, Alessandro Bertini, Francesco Lanzaro, Luigi Candela, Christian Corsini, Massimiliano Raffo, Fausto Negri, Ludovica Cella, Margherita Fantin, Paolo Capogrosso, Francesco Montorsi, and Andrea Salonia Luca BoeriLuca Boeri More articles by this author , Edoardo PozziEdoardo Pozzi More articles by this author , Federico BelladelliFederico Belladelli More articles by this author , Giuseppe FallaraGiuseppe Fallara More articles by this author , Simone CilioSimone Cilio More articles by this author , Alessandro BertiniAlessandro Bertini More articles by this author , Francesco LanzaroFrancesco Lanzaro More articles by this author , Luigi CandelaLuigi Candela More articles by this author , Christian CorsiniChristian Corsini More articles by this author , Massimiliano RaffoMassimiliano Raffo More articles by this author , Fausto NegriFausto Negri More articles by this author , Ludovica CellaLudovica Cella More articles by this author , Margherita FantinMargherita Fantin More articles by this author , Paolo CapogrossoPaolo Capogrosso More articles by this author , Francesco MontorsiFrancesco Montorsi More articles by this author , and Andrea SaloniaAndrea Salonia More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003291.06AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Patient’s characteristics at first medical evaluation for a specific sexual dysfunction (SD) are correlated to the public awareness towards the specific disease and the availability of novel treatments. We aimed to assess the clinical characteristics of patients presenting for premature ejaculation (PE) as their primary medical complaint over a 15-year time frame. METHODS: Data from 257 sexually active, heterosexual men seeking first medical help for primary PE at a single sexual medicine academic clinic between 2008 and 2022 were analysed. Clinical data and serum hormones were collected. At baseline all patients completed the International Index of Erectile Function (IIEF), the Beck Inventory for Depression (BDI), and the Premature Ejaculation Diagnostic Tool (PEDT). Relationship status was categorized as: single vs. stable sexual relationship. Descriptive statistics and linear regression analyses were used to describe the whole cohort. RESULTS: Median (IQR) age at presentation was 32 years. Of all, 182 patients reported some degree of erectile dysfunction (ED) according to IIEF-EF scores. Median baseline PEDT and BDI score were 14 and 7, respectively. Median total testosterone and TSH values were 5.2 ng/ml and 1.6 mUI/L, respectively. Across the 15-year time frame, patient’s age at presentation significantly decreased over time (p<0.001). Furthermore, depressive symptoms at BDI (p<0.001) and PE severity as scored with the PEDT (p<0.001) linearly decreased overtime. When segregating the whole cohort into 5-year groups, age at presentation decreased from 2008-2012 to 2013-2017 (p=0.04) and further decreased between 2018-2022 (p=0.01). Similarly, baseline BDI scores decreased from 2008-2012 to 2018-2022 (all p<0.001). PE severity at first assessment was stable between 2008-2012 to 2013-2017 but decreased thereafter. Patients in a stable couple relationship more frequently asked for medical attention for PE between 2018-2022 compared to 2013-2017 and 2008-2012. CONCLUSIONS: Findings from this study showed that PE patients characteristic at first presentation has changed throughout the last 15 years. Of note, age, PE severity and depressive symptoms showed a significant decline overtime. Men in a stable sexual relationship were more likely to seek medical attention for PE in recent years. These results probably reflect the increased public awareness of PE; therefore, patients request PE consultation at younger age, with initial symptoms and with fewer psychological bother related to this condition. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e623 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Luca Boeri More articles by this author Edoardo Pozzi More articles by this author Federico Belladelli More articles by this author Giuseppe Fallara More articles by this author Simone Cilio More articles by this author Alessandro Bertini More articles by this author Francesco Lanzaro More articles by this author Luigi Candela More articles by this author Christian Corsini More articles by this author Massimiliano Raffo More articles by this author Fausto Negri More articles by this author Ludovica Cella More articles by this author Margherita Fantin More articles by this author Paolo Capogrosso More articles by this author Francesco Montorsi More articles by this author Andrea Salonia More articles by this author Expand All Advertisement PDF downloadLoading ...