Abstract

Mortality rate of acute kidney injury in SARS, MERS, and COVID-19 infection: a systematic review and meta-analysis

Highlights

  • Acute kidney injury (AKI), a predictor for poor clinical outcomes, has been reported as a severe complication of different coronavirus infections, including novel coronavirus disease 2019 (COVID-19) [1]

  • We report the mortality rate from AKI in severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and COVID-19 infections as proportions with 95% confidence interval (CI) based on random effects model, represented by forest plot

  • We found the mortality rate of AKI was highest in SARS (86.6%; 95%CI: 77.7–93.5), followed by COVID-19 (76.5%; 95%CI: 61.0–89.0) and MERS (68.5%; 95%CI: 53.8–81.5)

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Summary

Introduction

Acute kidney injury (AKI), a predictor for poor clinical outcomes, has been reported as a severe complication of different coronavirus infections, including novel coronavirus disease 2019 (COVID-19) [1]. Reference lists of included, published, systematic reviews identified in the search were screened for additional studies. Review articles, or studies without reports of AKI mortality.

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