Abstract
Molecular Characterization of Human Respiratory Adenoviruses Infection in Xining City, China In 2018
Highlights
Dear Editor, Adenoviruses are non-enveloped, double-stranded DNA viruses belonging to the Adenoviridae family
Human adenovirus (HAdV) infection is mild and self-limited in the healthy individuals, it can be life-threatening in immune-compromised patients (Echavarria 2008)
HAdVs are playing an important role in the respiratory infections, which are responsible for several lower respiratory tract diseases
Summary
Received: 18 March 2020 / Accepted: 5 August 2020 / Published online: 14 September 2020. Our previous study showed that the species HAdV-B3, HAdV-C1 and HAdV-C2 were the prevalent HAdV types in children in Xining City during 2016–2017 (Yu et al 2019), which was a little different from the strains circulating in other. We performed active surveillance for HAdV infections based on the hexon and fiber gene sequencing in Xining City. This knowledge would benefit for better understanding the prevalence and molecular evolution of HAdVs and might assist with the effective prevention and control of respiratory adenoviruses infection in Xining City. The samples were detected and isolated for HAdVs and performed hexon and fiber gene sequencing according to previous methods (Yu et al 2019).
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