Abstract

Some recent developments in the use of molecular logic gates as fluorescent sensors are described. The discussion is classified in terms of the Boolean logical assignment of the sensor system. Even simple fluorescent sensors can be recognized as single-input logic gates. Several YES gates launch the analysis of examples. A consideration of various sensors driven by double inputs and higher multiple inputs then follows. Attention is particularly drawn to the appearance of double-input logical sensor molecules, which successfully operate within living cells—a milieu where conventional semiconductor-based logic devices would struggle on the grounds of compatibility and size. The value of molecular logical thinking in the understanding of fluorescent sensor behavior is emphasized throughout.

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