Abstract
Objective To evaluate the efficacy of modified Soave procedure combined with colon plication for the treatment of Hirschsprung's disease (HD) in children.Methods Between July 2005 and August 2009,32 HD patients of the plication group underwent modified Soave procedure combined with colon plication at this center.Another 32 patients who underwent modified Soave procedure were enrolled as the controls.The pathological examinations,follow-up,barium enema,anorectal manometry,and anorectal function were retrospectively reviewed and analyzed to evaluate the surgical efficacy.Results Of the 32 patients of the plication group,26 had normal ganglion cells at both ends of the dilated intestine,and decreased ganglia number and ganglia degeneration were found on the other 6 patients.However,among the 32 control patients,decreased ganglia number and ganglia degeneration was only found on 4 patients.Rectoscopy suggested that mucosa rugae caused by colon plication could eventually disappear half a year after the surgery.On patients' barium enema radiography,no dilated intestines were observed.No difference of the defecation function scores between the plication group and control group at 1 year after operation was found (defecation function score,6.6 ± 1.3 vs 6.8 ±1.2).Moreover,there was no difference of high pressure zone length (2.0 ± 0.7 cm vs 1.9 ± 0.6 cm),anal canal resting pressure (53.1 ± 3.9 mmHg vs 52 ± 4.7 mmHg) and sensation threshold (30～55 ml vs 35～60 ml) between the 2 groups 1 year after operation.Postoperative complications included anastomotic stenosis was noted on 1 patients of the placation group,1 of the plication group and 1 control patient had mild soiling.Conclusions Modified Soave procedure combined with colon plication improves the defecation function of the HD patients. Key words: Hirschsprung disease; Modified Soave; Follow-up studies
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call