Abstract

Over the past years, biomaterials-based nano cues with multi-functional characteristics have been engineered with high interest. The ease in fine tunability with maintained compliance makes an array of nano-bio materials supreme candidates for the biomedical sector of the modern world. Moreover, the multi-functional dimensions of nano-bio elements also help to maintain or even improve the patients’ life quality most securely by lowering or diminishing the adverse effects of in practice therapeutic modalities. Therefore, engineering highly efficient, reliable, compatible, and recyclable biomaterials-based novel corrective cues with multipurpose applications is essential and a core demand to tackle many human health-related challenges, e.g., the current COVID-19 pandemic. Moreover, robust engineering design and properly exploited nano-bio materials deliver wide-ranging openings for experimentation in the field of interdisciplinary and multidisciplinary scientific research. In this context, herein, it is reviewed the applications and potential on tissue engineering and therapeutics of COVID-19 of several biomaterials. Following a brief introduction is a discussion of the drug delivery routes and mechanisms of biomaterials-based nano cues with suitable examples. The second half of the review focuses on the mainstream applications changing the dynamics of 21st century materials. In the end, current challenges and recommendations are given for a healthy and foreseeable future.

Highlights

  • Nano-biomaterials have become a useful tool for medical applications for several reasons that include compatibility and novel effects due to nanoscale

  • Modern medicine has incorporated nanotechnology into two major topics of general concern, tissue engineering and novel viruses, which were chosen in this review due to significant cases and impact (Torres-Sangiao et al, 2016; van Rijn and Schirhagl, 2016; Kapat et al, 2020)

  • The presented work explores the most prominent alternatives focused on modern medicine applied in tissue engineering, as well as therapeutics and vaccines for COVID-19 disease

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Summary

INTRODUCTION

Nano-biomaterials have become a useful tool for medical applications for several reasons that include compatibility and novel effects due to nanoscale. Modern medicine has incorporated nanotechnology into two major topics of general concern, tissue engineering and novel viruses, which were chosen in this review due to significant cases and impact (Torres-Sangiao et al, 2016; van Rijn and Schirhagl, 2016; Kapat et al, 2020). Biomaterials compromise the group of substances that either are produced by living organisms or highly compatible In this matter, numerous research work has been done to test and use the materials in modern medicine. The presented work explores the most prominent alternatives focused on modern medicine applied in tissue engineering, as well as therapeutics and vaccines for COVID-19 disease. Multidimensional applications refer to the inclusion of several materials, drugs, geometries, and other characteristics in the nano biomaterial cues for desired multipurpose

DEFINING NANOSTRUCTURES
Bulk nanomaterials Nanocomposites
MECHANISMS OF THE MAIN ROUTES FOR DRUG DELIVERY
Gas Exchange Regions
Findings
MODERN WORLD APPLICATIONS
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