Abstract
Bovine lymphosarcoma is a neoplasm of lymphocytes that is commonly associated with bovine leukemia virus (BLV). BLV can be transmitted both vertically and horizontally, and transmission is highly dependent on farm control measures. BLV-induced tumors usually arise from the CD5+ IgM+ B-cell subpopulations. Clinical signs associated with development of lymphosarcoma are highly variable. This is because the clinical symptoms observed depend on the location of the tumors and the affected organs. BLV has been eradicated in over 20 countries via traditional antibody testing and slaughter methods. This case review looks at a 6-year-old, angus beef cow that presented to the hospital for sudden death. Necropsy and histopathological examination revealed a marked lymphadenopathy and lymphocytic infiltration of multiple organs, consistent with bovine lymphosarcoma.
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