Abstract

Biolasers obtained from biomaterials are attracting a wealth of interest for their potential as future biosensors with enhanced sensitivity, and advanced cell tracking. Here, miniature biolasers are reported, which are formed by bovine serum albumin (BSA) protein and biosourced polysaccharides derived from land plants such as cellulose and pectin. Using a green processing route aided by simple emulsions, solid‐state microspheres with diameters of 15–100 µm are fabricated and utilized as whispering gallery mode lasers with thresholds of a few µJ mm–2 and quality factors of up to 3000. Furthermore, BSA microlasers are found to be compatible with cell growth and resistant to the aqueous environment of cell culture media. This environmentally friendly and biocompatible design shows promise for future implantable biosensing devices opening a path between laser science and medicine.

Highlights

  • HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not

  • Miniature biolasers are reported, which are formed by bovine serum albumin (BSA) protein and biosourced polysaccharides derived from land plants such as cellulose and pectin

  • We report on two Optical biosensors, which are label-free and sensitive, have been classes of biopolymers, proteins, such as bovine serum albumin widely used in the life sciences.[1]

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Summary

Introduction

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The laser of optical devices.[26] Pectin and cellulose are biodegradable is obtained by free-space excitation and the lasing emission is and sustainable biosourced polysaccharides derived from land directly used for sensing applications, such as refractive index plants.[27] Besides their key roles in plant growth, morphology, change in the medium outside a cavity.[5,6] WGM lasers have and development,[28] these polysaccharides have recently picked been recently integrated to living cells for intracellular sensing up considerable attention for the elaboration of a wide range and cell tracking, which opens a new frontier of biotechnology.[7,8] of biomaterials and biocompatible devices.[29,30,31,32] With regards

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