Abstract
Abstract A simple method for the determination of isoproterenol in urine and plasma by high-performance liquid chromatography coupled with an automated trihydroxyindole method is described. No pre-purification procedures are required. The sensitivity was 0.2 pmol and the average recoveries of isoproterenol added to plasma and urine were 89% and 101%, respectively. The method has been applied successfully to clinical samples.
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