Abstract
1. 1. The rapid incorporation of label from intravenously administered serum-bound 9(10)-mono- and 12-monohydroxystearic acids into palmitic, stearic and octadecenoic acids in the intact rat has been demonstrated. 2. 2. Analysis of label distribution in the newly formed non-hydroxy acids, following different labeling of the injected monohydroxystearic acids, indicates that breakdown to, and resynthesis from, acetate accounted for this conversion. 3. 3. No evidence was found for a specific dehydration of monohydroxystearic acids to the unsaturated analogs. 4. 4. The monohydroxystearic acids were extremely rapidly broken down: less than one-fifth could be recovered as such from the whole rat 5 min after intravenous injection.
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