Abstract
We have developed a system with multimodality that monitors objective biomarkers for screening the mental distress in the office. A field study using a prototype of the system was performed over four months with 39 volunteers. We obtained PC operation patterns using a PC logger, sleeping time and activity levels using a wrist-band-type activity tracker, and brain activity and behavior data during a working memory task using optical topography. We also administered two standard questionnaires: the Brief Job Stress Questionnaire (BJS) and the Kessler 6 scale (K6). Supervised machine learning and cross validation were performed. The objective variables were mental scores obtained from the questionnaires and the explanatory variables were the biomarkers obtained from the modalities. Multiple linear regression models for mental scores were comprehensively searched and the optimum models were selected from 2,619,785 candidates. Each mental score estimated with each optimum model was well correlated with each mental score obtained with the questionnaire (correlation coefficient = 0.6–0.8) within a 24% of estimation error. Mental scores obtained by means of questionnaires have been in general use in mental health care for a while, so our multimodality system is potentially useful for mental healthcare due to the quantitative agreement on the mental scores estimated with biomarkers and the mental scores obtained with questionnaires.
Highlights
Mental disorders are of significant concern in terms of public health and economic development and social welfare [1]
We previously developed a PC logger, a wrist-band type activity tracker, and a wearable optical topography as a non-invasive brain activity sensor
The brain activity measured by optical topography during working memory tasks was affected by mood state [7,8,9]
Summary
Mental disorders are of significant concern in terms of public health and economic development and social welfare [1]. We previously developed a PC logger, a wrist-band type activity tracker, and a wearable optical topography as a non-invasive brain activity sensor. These have been independently used in several studies on mental healthcare application. The brain activity measured by optical topography during working memory tasks was affected by mood state [7,8,9]. The optical topography measurement was applied to return-to-work trainees in remission of mental disorders with depressive symptoms [10]. We introduce a multimodality data acquisition system we developed to combine these devices for monitoring multilateral conditions of mental health. The combination of behavioral and brain measurements is a novel approach
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