Abstract
Melkersson-Rosenthal syndrome is a rare disorder characterized by the triad of recurrent or persist orofacial edema, relapsing facial paralysis and fissured tongue. The syndrome does not always manifest in the complete triad and the diagnosis is often difficult. Here, we report a 24-year-old man presented with recurrent orofacial swelling and facial paralysis. The motor nerve conduction test showed reduction of the amplitude of compound muscle action potential of his facial nerve. The magnetic resonance imaging revealed a T1 gadolinium-enhancement along mastoid segment of left facial nerve. The biopsied specimens from the eyelid revealed a non-necrotizing granulomatous lymphohistiocytic infiltration surrounding the lymphatic duct and branches of his facial nerve. Melkersson-Rosenthal syndrome was diagnosed and the orofacial edema and facial paralysis resolved gradually after treatment with corticosteroid and azathioprine.
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