Abstract
Nowadays, there are a number of respiratory illnesses that directly affect children. Exhaled nitric oxide measurement (FeNO) is one of the modern methods of investigation used for diagnosing and controlling allergic eosinophilic airway inflammation. It is a simple, painless and time-saving method for the patient. Because of its non-invasiveness and simplicity, it is a valuable diagnostic method, especially in younger children. Measurement of FeNO is a recognized biomarker and an accurate quantitative indicator in the detection, assessment and monitoring of airway inflammation, including asthma. However, only a few studies assess the relationship between FeNO and level of air pollution. The aim of our study is to determine the relationship between FeNO in third-grade students of primary schools and the level of air pollution in Ruzomberok. 146 children aged 8-10 years were included in the research. This is the first stage of a wider research project involving FeNO measurements in children at different times of the year. The goal of the research is to determine the concentration of FeNO in the studied group of children in the autumn when air pollution is lower than in second stage which is observed in winter. The study showed elevated values of FeNO>20 ppb in 11% of the tested children and correct values <20 ppb in 89% of them. Level of average air pollution in survey days for PM10 ranged from 23 to 40 μg/m3 and for NO2 – from 28 to 44 μg/m3. The study shows that the significant majority of children have normal levels of nitric oxide in the exhaled air when air pollution is low. Analysis of the second phase of FeNO measurements in winter, when air pollution was higher, will allow to compare the results and assess the correlation between the FeNO value and air pollution.
Highlights
Measurement of nitric oxide in exhaled air in primary school children in Ružomberok
The first presence of NO in the exhaled air was confirmed by Gustafsson in 1991 and the first guidelines principles for the measurement of nitric oxide in exhaled air were published by the American Thoracic Society in 1999
MATERIALS AND METHODS OF RESEARCH Our study examined all third-grade children who were in school on the days of the research
Summary
Measurement of nitric oxide in exhaled air in primary school children in Ružomberok. CzubajKowal M., Friediger T., Hudáková Z., Sokołowski M., Walczak-Kapołka E., Aštaryová I., Lesňáková A. Exhaled nitric oxide measurement (FeNO) is one of the modern methods of investigation used for diagnosing and controlling allergic eosinophilic airway inflammation. It is a simple, painless and time-saving method for the patient. Дослідження показує, що значна частина дітей має нормальний рівень оксиду азоту в повітрі, що видихається, коли забруднення повітря низьке. Exhaled nitric oxide measurement (FeNO) is one of the modern, simple and noninvasive method of investigation used for diagnosing and controlling eosinophilic inflammation. The aim of the study is to determine the relationship between the concentration of nitric oxide in exhaled air in children of the third grade of primary school and the level of air pollution in Ružomberok. According to modelling and analysis results, it contributes to average annual PM10 and NO2 concentrations in ambient air [7]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
