Abstract
The measurement of nitric oxide (NO) in exhaled air is used in diagnostics and monitoring of the pathologies in the respiratory system but also in the oral cavity. Researchers have shown a huge increase of its level in asthma and diseases in the oral cavity. It seems reasonable to research the impact of pathologies in the oral cavity on the level of NO in exhaled air. The purpose of this study was to determine the impact of inflammation in the oral cavity (according to the material of dentures) on the level of nitric oxide in exhaled air. Three groups of patients were examined in this study. The hygiene of acrylic dentures, hard tissues, periodontal tissues, hygiene of the oral cavity, and level of NO in exhaled air were examined. Prosthetic stomatitis, denture plaque, tooth decay, poor sanitation and periodontitis increase levels of NO.
Highlights
In the etiology of oral cavity pathologies, the main impact is from dental plaque, which in cases of a poor hygiene shows adhesion to hard tissues, soft tissues and acrylic dentures.Tooth decay, one of the most common oral diseases, is another pathology associated with dental plaque
It is described as a pathological process in which bacteria release substances or secondary metabolites that stimulate cells in the oral cavity to produce cytokines which lead to local disease such as gingivitis, mucositis, and periodontitis
The study group consisted of 100 patients with severe carious process, not using prosthetic restorations, aged 25–65; 100 patients using upper and lower full dentures, aged 25–85; the control group consisted of 30 patients with no prosthetic restorations, no carious process, and with proper oral hygiene
Summary
One of the most common oral diseases, is another pathology associated with dental plaque. It is described as a pathological process in which bacteria release substances or secondary metabolites that stimulate cells in the oral cavity to produce cytokines which lead to local disease such as gingivitis, mucositis, and periodontitis. This chronic inflammation can lead to systemic diseases—for example endocarditis [1,2,3]. NF-k B transcripts for the iNOS and interactions of methacrylates with cells of the oral cavity [4,5,6]
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