Mathematical Modeling of Type -2 Diabetes Mellitus as a Risk Factor for Cancer

Abstract

Diabetes, a fifth leading disease in terms of causing death, is a complex syndrome, characterized by the altered metabolism of proteins, fats, and carbohydrates result in the raising of blood glucose level to more than 180 mg/dl cause a condition called Hyperglycemia. Many shreds of evidence are suggesting the positive relationship between diabetes and cancer means diabetic patients are more prone to cancer. Risk factors associated with type 2 diabetes and cancer share some common pathophysiologies as well as treatments and thus type-2 diabetes mellitus may be a predisposing factor for Cancer. The work proposes a generalized mathematical model whose numerical solution depicts the risk of cancer to the one having type-2 diabetes mellitus. In type-2 diabetes, the body neglects to react to the insulin produced by the body itself. A system of differential conditions is utilized for depicting these changes. This model incorporates the concentration of glucose, insulin and cancer growth cells. Taking everything into account, the possibility of having cancer is more in the individuals having longstanding type-2 diabetes than those who do not have diabetes. In the work, we propose a numerical model for the risk of disease to a patient having type 2 diabetes mellitus for quite a while.