Abstract
Abstract Malignant hyperthermia (MH) is an autosomal dominantly inherited disorder characterized by skeletal muscle hypermetabolism following exposure to halogenated anesthetics and depolarizing muscle relaxants such as succinylcholine. The sustained muscle contraction produces a depletion of adenosine triphosphate, dramatically increasing oxygen consumption, carbon dioxide production, and heat. We present the rare case report of MH diagnosed intraoperatively posted for an open reduction and internal fixation surgery of the right mid-shaft of femur fracture. Unfortunately, the patient developed MH and succumbed. In every hospital set-up where MH-triggering anesthetics are administered, an adequate stock of dantrolene and other medications and rescue equipment must be available to treat the MH crisis.
Published Version
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