Magnetic nanomaterials as green and recoverable nanocatalysts: Research on synthesis of benzimidazole derivatives

Abstract

Research on benzimidazole derivatives is always an attractive challenge among synthetic chemists because benzimidazole derivatives are very key and important components in the structure of many drugs, biological active molecules, and natural products. Benzimidazole derivatives are very interesting because of their valuable biological and medicinal activities, such as anti-bacterial, anti-cancer, anti-tuberculosis, anti-fungal, pain killer, and anti-HIV activities. During the last decade, most reports in the field of catalysts have been related to magnetic nanocatalysts, which shows the high popularity and remarkable efficiency of this type of catalyst in performing chemical reactions. Magnetic nanocatalysts are ideal catalysts both from the point of view of green chemistry and economically because they are easily separated from the reaction mixture and have significant catalytic activity. In this review article, we have summarized the methods presented on the synthesis of various benzimidazole derivatives based on the use of magnetic nanomaterials as green recoverable catalysts.