Magnesium sulfate combined with nimodipine in treatment of pregnancy-induced hypertension

Abstract

Objective To investigate the clinical efficacy of magnesium sulfate combined with nimodipine in the treatment of pregnancy-induced hypertension. Methods 80 patients with pregnancy-induced hypertension treated at our hospital from March, 2012 to March, 2015 were selected and were randomly divided into an observation group and a control group, 40 cases for each group. The control group were treated with magnesium sulfate and other conventional methods for 1 month. The observation group were treated with magnesium sulfate nimodipine for 1 month. The clinical efficacies were evaluated and compared. Results After the treatment, the blood pressure conditions were obviously improved in the observation group and were better in the observation group than in the control group. The total efficacy was 95.5% in the observation group and was 71.4% in the control group, with a statistical difference (P<0.05). After childbirth, the neonatal conditions were better in the observation group than in the control group, with statistical differences(P<0.05). There were statistical differences in pregnancy outcomes between these two groups (P<0.05). Conclusions Magnesium sulfate combined with nimodipine in the treatment of pregnancy-induced hypertension is effective and safe and worth being clinically studied and generalized. Key words: Magnesium sulfate; Nimodipine; Pregnancy-induced hypertension; Effect