Abstract
This chapter provides an overview of the lumpy skin disease (LSD) virus. This virus belongs to the Poxviridae family and causes multiple nodules in the skin and affects mucous membranes. It also causes lymphadenitis. The hosts to the LSD virus are cattle and buffalos. The virus has not been reported outside of Africa. Histopathology, tissue culture cytopathology, and fluorescent antibody are some of the diagnostic techniques of LSD. The virus has been compared with the Allerton, Bovine mammillitis virus, which produces lesions similar to the early stages of LSD. Immunofluorescent assay and the micro-serum neutralization test are both good serological tests for the diagnosis of the LSD virus. The chapter also highlights the key development and historical movement of the virus. The LSD virus was first described in the southern regions of Africa and Madagascar in 1929. The Neethling virus is the cause of it. Vaccines for LSD have been developed.
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