Logistic regression analysis of risk factors of Type 2 diabetes mellitus complicated with cardiovascular disease factors

Abstract

Objective To explore the main risk factors of type 2 diabetes mellitus(T2DM)complicated with cardiovascular disease(CVD). Methods The T2DM of 128 cases of CVD associated with CVD group were selected, the patients with T2DM 107 cases were selected as control group, used Logistic regression method for the analysis of the risk factors of concurrent CVD. Results The risk of CVD in patients with a family history of T2DM was 1.535 times of that of the other patients(OR=1.535,95%CI=1.145,2.057,P=0.036), the vegetarian diet patients was 41.3%(OR=0.413,95%CI=0.210,0.815,P=0.024),in patients with hypertension was 2.077 times(OR=2.077,95%CI=1.301,2.813,P=0.010).T2DM patients with TG,PBG,LDL-C,HDL-C per 1mmol/L rise,the risk of concurrent CVD was 1.192 times of that of the other patients(OR=1.192,95% CI 1.012,1.372,P=0.023),1.125 times(OR=1.125,95%CI=1.043,1.218,P=0.028),1.712 times(OR=1.712,95%CI=1.203,2.231,P=0.009)and 42.6%(OR=0.426,95%CI=0.239,0.776,P=0.011);Hb A1c increased every 1%,the risk of concurrent CVD was 1.284 times of that of theother patients(OR=1.284,95% CI=1.132,1.413,P=0.013);BMI increased by 1kg/m2,the risk of concurrent CVD was 1.508 times of that of the other patients(OR=1.508,95%CI=1.143,1.825,P=0.026);C2 increased by 1m L/mm Hg×100,the risk was the other patient's 33.9%(OR=1.508,95%CI=1.143,1.825,P=0.026). Conclusion Family history of T2DM, hypertension, TG,PBG,LDL-C,Hb A1c and BMI are major risk factors for T2DM with CVD;vegetarian diet,HDL-C and C2 are protective factors. Key words: Diabetes mellitus, type 2; Cardiovascular disease; Risk factors; Concurrent