Abstract
ABSTRACT
 
 Cod liver oil as a source PUFA (Polyunsaturated Fatty Acid) has very diverse and complex benefits, including for heart health. This study aimed to improve the lipid profile of male local rabbit which was fed commercial supplementation of cod liver oil. The experimental design used was Completely Randomized Design (RAL) with four feed treatments, ie commercial feed without supplementation of cod liver oil (P0) as control, commercial feed supplemented by cod liver oil 1.5% (P1), commercial feed supplemented by oil liver of 3% cod (P2) and commercial feed supplementation of cod liver oil 4.5% (P3).Each treatment consists of eight rabbits. The variables observed were total cholesterol, triglyceride, LDL, and HDL levels. The data obtained were analyzed with ANOVA and if significantly different were tested further with DMRT. The results showed that supplementation of cod liver oil with different levels in commercial feed showed significantly different results (P <0.05) on total cholesterol, triglyceride, LDL, and HDL levels of local rabbit. It can be concluded that supplementation of cod liver oil in commercial feed to the extent 4.5% capable repair the lipid profile of male local rabbit because it can decreased total cholesterol levels, decrease triglycerides levels, decreased LDL levels, and increased HDL levels.
Highlights
Cod liver oil as a source PUFA (Polyunsaturated Fatty Acid) has very diverse and complex benefits, including for heart health
The results showed that supplementation of cod liver oil with different levels in commercial feed showed significantly different results (P
Suplementasi minyak hati ikan kod pada pakan komersial sampai taraf 4,5% mampu memperbaiki profil lipid kelinci jantan lokal, yaitu dapat menurunkan kadar kolesterol total, menurunkan kadar trigliserida, menurunkan kadar LDL, dan meningkatkan kadar HDL
Summary
Hewan coba yang digunakan adalah kelinci jantan lokal pradewasa sebanyak 32 ekor, umur 12 minggu, dengan rerata berat badan 1034,88 g s.d. 1035,41 g. Prosedur percobaan dengan menggunakan kelinci sebagai hewan percobaan telah dinyatakan Laik Etik (Ethichal Clearance) oleh Komisi Etik Penggunaan Hewan dalam Penelitian dan Pendidikan, Fakultas Kedokteran Hewan Universitas Udayana, Denpasar. Pakan yang digunakan adalah pelet pakan komersial yang diproduksi oleh P.T. Japfa Comfeed Indonesia dan diperoleh dari toko pakan ternak di Beringkit Mengwi Badung. Minyak hati ikan kod yang digunakan adalah emulsi minyak hati ikan kod yang diproduksi oleh P.T. Merck Tbk, Jakarta dan diperoleh dari apotik di Tabanan. Tiga puluh dua ekor kelinci jantan lokal diacak menjadi empat perlakuan pakan termasuk kontrol dan masing-masing perlakuan dengan delapan ulangan. Masing-masing perlakuan pakan yang diujikan adalah sebagai berikut P0 : kontrol (pakan komersial tanpa suplementasi minyak hati ikan kod) ; P1: pakan komersial disuplementasi minyak hati ikan kod 1,5%; P2 : pakan komersial disuplementasi minyak hati ikan kod 3% ; P3 : pakan komersial disuplementasi minyak hati ikan kod 4,5%
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