Lipid metabolism as microecological and systemic factor in the development of periodontal disease: a review

Abstract

Aim — analysis of modern ideas about the relationship between the state of lipid metabolism and periodontal diseases. Materials and methods. The study was carried out by means of an analytical review of publications of Russian and foreign scientific journals, in which the results of independent clinical and laboratory studies of this material from 2005 to 2019 were presented. Results. It has been established that the role of lipids in the composition of key bacteria, which are periodontopathogens, in the process of interaction of periodontopathogenic bacteria with periodontal tissue cells, as components of human body fluids in infectious and inflammatory periodontal diseases is in no doubt and is characterized by high pathogenetic significance. Conclusion. In general, we can conclude that the lipid metabolism of both periodontopathogenic bacteria and the macroorganism at the local and systemic level plays a significant role in the occurence and progression of periodontal diseases, and studies in this direction open up broad prospects for the development of clinical periodontology and the development of new drugs for treatment and prevention of so common pathology, which is capable of inducing systemic effects.