Abstract
A major feature of aging is a mounting incidence of organ failure. Heart failure is the major cause of death, and organ failure in general accounts for a large percentage of all age-related deaths. The ability to grow replacement organs in vitro or in vivo and to transplant them as needed would, by itself, address a great deal of the present morbidity and mortality associated with aging. In this chapter, we review present day successes in creating viable human organs that are functioning today in patients who need them as well as research that is leading to even greater capabilities for organ and tissue replacement in the future.
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