Learning from multi-model comparisons: Collaboration leads to insights, but limitations remain

Abstract

Neglected tropical diseases (known as NTDs) are a group of diseases predominantly affecting the poorest populations of the globe (sometimes called the ‘bottom billion’). The risk of disease is related to poor housing, poor sanitation and poor health systems as well as the environmental suitability of tropical areas. The NTDs are not a well-defined group, and comprise a variety of pathogens with different transmission routes, life cycles and behavioural risk factors, although they are similar in that they are currently relatively hard to diagnose. The host population factors and relatively poor surveillance data present particular challenges for providing transmission dynamics models. This collection reflects the current state-of-the-art for modelling NTDs, as well as judging on the suitability of models to provide quantitative policy advice.