Abstract
The kinetics of the reactions of 2- and 4-amino-, -methylamino-, and -dimethylamino-pyridine methiodides with hydroxide ions in water have been studied. At 20 °C, 2-dimethylaminopyridine methiodide was 8.5 × 103 times more reactive than its 4-isomer, owing mainly to a lower energy of activation (by 6.4 kcal mol–1). The 2- and 4-dimethylaminopyridine methiodides were 2.3 × 10–4 and 3.1 × 10–6 times less reactive than their chloroanalogues. The reaction of 2-methylthiopyridine methiodide with hydroxide ions was found to proceed via a two-step process.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of the Chemical Society, Perkin Transactions 2
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
