Abstract
Leptospirosis is a zoonotic disease caused by Leptospira spp infecting human body through contact with urine of infected animals. Although leptospirosis has been reported in Indonesia, however there is no data of the disease in some regencies of Central Sulawesi Province , particularly in Toli-Toli, Tojo Una-una and Parigi Moutong . The clinical diagnosis of leptospirosis is difficult to be determined. As a result, the disease report is lower than the real condition in the field. This research was designed using an observational descriptive cross-sectional study. Samples were collected by purposive sampling based on geographic stratification and ecosystems as well as line transect method. The present Leptospira spp in rats were confirmed by Polymerase Chain Reaction (PCR) and Microscopic Agglutination Test (MAT). The results demonstrated that Leptospira spp was successfully detected in rats distributed in various ecosystems (far and near settlements) in the three regencies. The infected rats were Bunomys sp., Rattus sp., Maxomys whiteheadi , Rattus tanezumi , Maxomys cf. hellwaldii , Bunomys penitus , Rattus facetus , Maxomys cf. musschenbroekii , Mus musculus, Rattus hoffmanni , and Rattus exulans . The results also indicated that the risk of leptospirosis attacking in human transmitted by rats in those three regencies was relatively high.
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