Abstract
Rats are the main natural infectious host of leptospirosis to human. Rattus norvegicus (rats) and Rattus tanezumi (house mice) are two types of domestic rats that related with leptospira infection in the world. They are played the main role major leptospirosis transmission to human than others. This study aims to determine seroprevalence of Leptospira of R. norvegicus and R. tanezumi based of the sex and age. The method of study was trapping rats in the Miroto village (Semarang) and Tridonorejo village (Demak). LeptoTec Dri-Dot test has used after take blood of the rats intracardially and weight eye lens used to determinan age of the rats. The results showed seroprevalence of Leptospira in R. norvegicus were 66,67% and R. tanezumi were 24,39%. Seroprevalence of Leptospira in R. norvegicus females were 71,43% and R. norvegicus males were 60%. Seroprevalence of Leptospira in R. tanezumi females were 21,43% and R. tanezumi male were 30,77%. Based of age showed seroprevalence of Leptospira was highest in R. norvegicus and R.tanezumi adult than R. norvegicus and R. tanezumi young.
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